You don’t need to compile python for Mac/Windows/Linux. It is an interpreted language, so you simply need to have the Python interpreter installed on the system of your choice (it is available for all three platforms).

As for a GUI library that works cross platform, Python’s Tk/Tcl widget library works very well, and I believe is sufficiently cross platform.

Tkinter is the python interface to Tk/Tcl

From the python project webpage:

Tkinter is not the only GuiProgramming
toolkit for Python. It is however the
most commonly used one, and almost the
only one that is portable between
Unix, Mac and Windows

Since python is installed on nearly every non-Windows OS by default now, the only thing you really need to make sure of is that all of the non-standard libraries you use are installed.

Having said that, it is possible to build executables that include the python interpreter, and any libraries you use. This is likely to create a large executable, however.

MacOS X even includes support in the Xcode IDE for creating full standalone GUI apps. These can be run by any user running OS X.

An alternative tool to py2exe is bbfreeze which generates executables for windows and linux. It’s newer than py2exe and handles eggs quite well. I’ve found it magically works better without configuration for a wide variety of applications.

I’m not sure that this is the best way to do it, but when I’m deploying Ruby GUI apps (not Python, but has the same “problem” as far as .exe’s are concerned) on Windows, I just write a short launcher in C# that calls on my main script. It compiles to an executable, and I then have an application executable.

For the GUI itself:

PyQT is pretty much the reference.

Another way to develop a rapid user interface is to write a web app,
have it run locally and display the app in the browser.

Plus, if you go for the Tkinter option suggested by lubos hasko
you may want to try portablepy to have your app run on Windows environment
without Python.

Another system (not mentioned in the accepted answer yet) is PyInstaller, which worked for a PyQt project of mine when py2exe would not. I found it easier to use.

http://www.pyinstaller.org/

Pyinstaller is based on Gordon McMillan’s Python Installer. Which is no longer available.

There’s also PyGTK, which is basically a Python wrapper for the Gnome Toolkit. I’ve found it easier to wrap my mind around than Tkinter, coming from pretty much no knowledge of GUI programming previously. It works pretty well and has some good tutorials. Unfortunately there isn’t an installer for Python 2.6 for Windows yet, and may not be for a while.

# I'd use tkinter for python 3

import tkinter

tk = tkinter.Tk()
tk.geometry("400x300+500+300")
l = Label(tk,text="")
l.pack()
e = Entry(tk)
e.pack()

def click():
    e['text'] = 'You clicked the button'

b = Button(tk,text="Click me",command=click)
b.pack()

tk.mainloop()

# After this I would you py2exe
# search for the use of this module on stakoverflow
# otherwise I could edit this to let you know how to do it

py2exe

Then you should use py2exe, for example, to bring in one folder all the files needed to run the app, even if the user has not python on his pc (I am talking of windows… for the apple os there is no need of an executable file, I think, as it come with python in it without any need of installing it.

Create this file

1. Create a setup.py

---

with this code:

from distutils.core import setup
import py2exe

setup(console=['l4h.py'])

save it in a folder

2. Put your program in the same folder of setup.py
   put in this folder the program you want to make it distribuitable:
   es: l4h.py

ps: change the name of the file (from l4h to anything you want, that is an example)

3. Run cmd from that folder (on the folder, right click + shift and choose start cmd here)
4. write in cmd:>python setup.py py2exe
5. in the dist folder there are all the files you need
6. you can zip it and distribute it

Pyinstaller

Install it from cmd

**

pip install pyinstaller

**

Run it from the cmd from the folder where the file is

**

pyinstaller file.py

**

Update

Read this post to make an exe on windows with pyinstaller the proper way and with one file and images in it https://pythonprogramming.altervista.org/auto-py-to-exe-only-one-file-with-images-for-our-python-apps/

You can use appJar for basic GUI development.

from appJar import gui

num=1

def myfcn(btnName):   
    global num
    num +=1
    win.setLabel("mylabel", num)

win = gui('Test')

win.addButtons(["Set"],  [myfcn])
win.addLabel("mylabel", "Press the Button")

win.go()

See documentation at appJar site.

Installation is made with pip install appjar from command line.

PySimpleGUI wraps tkinter and works on Python 3 and 2.7. It also runs on Qt, WxPython and in a web browser, using the same source code for all platforms.

You can make custom GUIs that utilize all of the same widgets that you find in tkinter (sliders, checkboxes, radio buttons, …). The code tends to be very compact and readable.

#!/usr/bin/env python
import sys
if sys.version_info[0] >= 3:
    import PySimpleGUI as sg
else:
    import PySimpleGUI27 as sg

layout = [[ sg.Text('My Window') ],
          [ sg.Button('OK')]]

window = sg.Window('My window').Layout(layout)
button, value = window.Read()

As explained in the PySimpleGUI Documentation, to build the .EXE file you run:

pyinstaller -wF MyGUIProgram.py

!!! KIVY !!!

I was amazed seeing that no one mentioned Kivy!!!

I have once done a project using Tkinter, although they do advocate that it has improved a lot, it still gives me a feel of windows 98, so I switched to Kivy.

I have been following a tutorial series if it helps…

Just to give an idea of how kivy looks, see this (The project I am working on):

And I have been working on it for barely a week now !
The benefits for Kivy you ask? Check this

The reason why I chose this is, its look and that it can be used in mobile as well.

There’s three things you could do:

The first thing is to find a GUI Designer that can launch its code as standalone applications like .exe files. I use a version of MatDeck (for people using GUI Designers I recommend MD Python Designer) as I believe(I use another version so I’m not too sure.) it allows me to convert the code to a standalone applications and by having it as such, there is no need to install the software on every PC that’s going to run the program.

The second option is partially bypassing the problem, launch the GUI as a web page. This would give you the most compatibility as most if not all OS can utilize it. Once again, you would need a GUI Designer that can convert its components into a web compatible format, I’ve done it once and I used the same version of MatDeck(Visionary Deck), I would not recommend MD Python Designer this time as I don’t know if it can turn its GUIs into websites using web assembly whereas Visionary Deck I’ve tried and tested. As with all things there are most likely other software this is just one I use frequently because I work a lot with Mathematics and Physics.

The third option is also kind of bypassing the problem but do it in Tkinter and just ensure you have a Python IDE or just plain old Python and run the code, this will launch the GUI. This is a good solution and maybe the simplest but I wouldn’t class it as the shortest or the best. If you only plan to switch between a few operating systems and computers this will probably be your best bet.