Python on Electron framework

You can use python-shell to communicate between Python and Node.js/Electron.

python-shell provides an easy way to run Python scripts from Node.js with basic and efficient inter-process communication and better error handling.

Using python-shell, you can:

• spawn Python scripts in a child process;
• switch between text, JSON and binary modes;
• use custom parsers and formatters;
• perform data transfers through stdin and stdout streams;
• get stack traces when an error is thrown.

In your terminal, make sure you are inside the root folder of your project and run the following command to install python-shell from npm:

npm install --save python-shell 

You can then simply run a Python shell using:

var pyshell =  require('python-shell');

pyshell.run('hello.py',  function  (err, results)  {
 if  (err)  throw err;
 console.log('hello.py finished.');
 console.log('results', results);
});

See more information from this tutorial

This is an update to the answer by @bluesummers that works for me on Jan 2, 2020.

1. Install Node (https://nodejs.org/en/download/) and python 3.

2. Install dependencies:

    pip install Flask
    npm install electron
    npm install request
    npm install request-promise

3. Create a directory for your project and create the following files in that directory:

main.js

const electron = require( "electron" );
const app = electron.app;
const BrowserWindow = electron.BrowserWindow;
electron.crashReporter.start( { companyName: "my company", submitURL: "https://mycompany.com" } );

var mainWindow = null;

app.on(
    "window-all-closed",
    function()
    {
        // if ( process.platform != "darwin" )
        {
            app.quit();
        }
    }
);

app.on(
    "ready",
    function()
    {
        var subpy = require( "child_process" ).spawn( "python", [ "./hello.py" ] );
        // var subpy = require( "child_process" ).spawn( "./dist/hello.exe" );
        var rp = require( "request-promise" );
        var mainAddr = "http://localhost:5000";

        var OpenWindow = function()
        {
            mainWindow = new BrowserWindow( { width: 800, height: 600 } );
            // mainWindow.loadURL( "file://" + __dirname + "/index.html" );
            mainWindow.loadURL( "http://localhost:5000" );
            mainWindow.webContents.openDevTools();
            mainWindow.on(
                "closed",
                function()
                {
                    mainWindow = null;
                    subpy.kill( "SIGINT" );
                }
            );
        };

        var StartUp = function()
        {
            rp( mainAddr )
            .then(
                function( htmlString )
                {
                    console.log( "server started!" );
                    OpenWindow();
                }
            )
            .catch(
                function( err )
                {
                    console.log( "waiting for the server start..." );
                    // without tail call optimization this is a potential stack overflow
                    StartUp();
                }
            );
        };

        // fire!
        StartUp();
});

package.json

{
    "name": "your-app",
    "version": "0.1.0",
    "main": "main.js",
    "scripts":
    {
        "start": "electron ."
    },
    "dependencies":
    {
        "electron": "*",
        "request": "^2.88.0",
        "request-promise": "^4.2.5"
    }
}

hello.py

from __future__ import print_function
# import time
from flask import Flask

app = Flask( __name__ )

@app.route( "/" )
def hello():
    return "Hello World! This is powered by a Python backend."

if __name__ == "__main__":
    print( "oh hello" )
    #time.sleep(5)
    app.run( host = "127.0.0.1", port = 5000 )

4. From within the project directory, run:

    npm start

With electron-django app I am developing I used pyinstaller to get my django app compiled, then just spawn its child process and it works, please notice pyinstaller may not recognize all modules or dist folder. there are plenty examples online on how to get a workaround for that filling the .specs file and amending the dist folder adding the files you may need.
pyinstaller usually tells you what went wrong in the terminal. hope it helps

There is a way to convert Streamlit (Python) applications to Electron now: https://github.com/whitphx/stlite/blob/main/packages/desktop-cli/README.md

Caution, all the packages you use need to have Python 3 wheels available for micropip to build your app

We have just released NiceGUI 1.2.0 which introduces “native” mode. This allows Electron-like capabilities by opening a native window on your desktop instead of a browser tab.

NiceGUI is an open-source Python library to write graphical user interfaces which run in the browser. It has a very gentle learning curve while still offering the option for advanced customizations. NiceGUI follows a backend-first philosophy: it handles all the web development details for you. You can focus on writing Python code.

python3 -m pip install nicegui

from nicegui import ui

ui.label('This is a Python desktop app')
ui.button('click me', on_click=lambda: ui.notify('a notification'))

ui.run(native=True)

Of course the app can also be packaged into an executable.